Add Histone H3 Lysine Methylation In Cognition And Mental Disability Problems

Histone-H3-Lysine-Methylation-In-Cognition-And-Mental-Disability-Problems.md

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+This family contains only one protein, SET7/9, which mono-methylates histone at H3K4 92 KMT7 was found to methylate, besides histone, a variety of non-histone proteins, together with p53, DNA methyltransferase 1 (DNMT1), [estrogen](https://www.social.svhub.de/jxsjaunita2826/lawyer-articles2011/wiki/Christopher+Lutz+Wants+To+Put+An+End+To+Amityville+Horror) receptor alpha (ERα), nuclear factor kappaB (NFκB), and elements of the TATA binding protein (TBP) complex, TBP-associated components TAF10 and TAF7 93 The consensus recognition sequence in substrates for SET7-mediated lysine methylation, Ok/R-S/T-Ok (target lysine is bold), can be acknowledged by the H3K4 demethylase KDM1A/LSD1, which is able to removing the methyl mark on most of those substrates 17 , ninety four Subsequently KMT7/KDM1A has emerged as a traditional mannequin for dynamic lysine methylation of each histone and non-histone proteins.
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